- Sublingual immunotherapy (SLIT) is a variation on allergen-specific immunotherapy (ASIT), which most of us refer to as allergy shots
- Sublingual means "under the tongue," and the treatment is delivered with a dispenser that sprays a few drops of allergen solution on the mucosa under the tongue; the drops are absorbed rough the moist tissue of the mouth and processed by specialized cells that help the immune system develop tolerance for specific allergens.
- The biggest benefit of SLIT over ASIT is no injections; probably the biggest drawback is that to be effective, the therapy must be administered daily, and sometimes several times a day.
- Uncontrolled studies on dogs show that SLIT is as effective as allergy shots, and dogs that for a variety of reasons can't tolerate injections also do well with sublingual administration.
- An additional options for allergic pets is regionally specific immunotherapy (RESPIT®), which is designed to be effective without the need for allergy testing